MODELS OF TOXOPLASMOSIS

MOUSE MODEL

Model developed in non-consanguineous mouse (Mus musculus) strains infected by Toxoplasma gondii oocysts.

Uses: Efficacy of new drugs and vaccines as "proof of concept".

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FELINE MODEL

Model developed in the definitive host (Felis silvestris catus).

Uses: Production of oocysts. Evaluation of drugs and vaccines.

PREGNANT OVINE MODEL

Model developed in pregnant sheep (Ovis aries) based on challenge with oocysts * during the second third of gestation.

Uses: Evaluation of drugs and vaccines.